On the relationship between instantaneous phase synchrony and correlation-based sliding windows for time-resolved fMRI connectivity analysis

M Pedersen; A Omidvarnia; A Zalesky; GD Jackson

Journal article

On the relationship between instantaneous phase synchrony and correlation-based sliding windows for time-resolved fMRI connectivity analysis

M Pedersen, A Omidvarnia, A Zalesky, GD Jackson

Neuroimage | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2018

DOI: 10.1016/j.neuroimage.2018.06.020

Abstract

Correlation-based sliding window analysis (CSWA) is the most commonly used method to estimate time-resolved functional MRI (fMRI) connectivity. However, instantaneous phase synchrony analysis (IPSA) is gaining popularity mainly because it offers single time-point resolution of time-resolved fMRI connectivity. We aim to provide a systematic comparison between these two approaches, on temporal, topological and anatomical levels. For this purpose, we used resting-state fMRI data from two separate cohorts with different temporal resolutions (45 healthy subjects from Human Connectome Project fMRI data with repetition time of 0.72 s and 25 healthy subjects from a separate validation fMRI dataset w..

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University of Melbourne Researchers

Andrew Zalesky Author

Graeme Jackson Author

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Grants

Awarded by NIH Blueprint for Neuroscience Research

Funding Acknowledgements

The primary fMRI data in this study was provided by the Human Connectome Project, WUMinn Consortium (1U54MH091657; Principal Investigators: David Van Essen and Kamil Ugurbil) funded by the 16 National Institutes of Health institutes and centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. We thank Mira Semmelroch and Magdalena Kowalczyk for acquisition of the fMRI validation data. This study was supported by the National Health and Medical Research Council of Australia (APP628952). The Florey Institute of Neuroscience and Mental Health acknowledges the strong support from the Victorian Government and in particular the funding from the Operational Infrastructure Support Grant. We also acknowledge the facilities, and the scientific and technical assistance of the National Imaging Facility (NIF) at the Florey node and The Victorian Biomedical Imaging Capability (VBIC). G Jackson is supported by the NHMRC practitioner's fellowship (APP1060312). A Zalesky is supported by the NHMRC Senior Research Fellowship B (APP1136649).